Putina S.N. 1
1 Saratov State Agrarian University Named After N.I. Vavilov
In this work we present the study of the effect of the «Gepasafe-plus» drug on the overall clinical condition, hematological and biochemical parameters, as well as the functional state of liver and kidney function in dogs and cats. To investigate the «Gepasafe-plus»drug 20 cats with diseases of the hepatobiliary system were picked up aged 8 to 15 years, and 30 dogs were chosen by analogy, between the ages of 6 to 7 months. In the course of the experiment all animals were kept under the same conditions, feeding was carried out with prepared rations. Duration of administration course was 21 days. Animals were divided into experimental and control groups. The findings of the experiment show that the effectiveness of the therapeutic measures in the experimental group was 100%, while the control group showed 90%. According to the results of the work, the administration of «Gepasafe-plus» in a therapeutic dose in test animals had a positive effect on the functional state of organs and body systems of dogs, which is confirmed by the results of clinical and laboratory research. The test also confirmed that the use of the»Gepasafe-plus»drug for 21 days in a double (from therapeutic) dose did not have any negative effect on physiological vital signs of dogs, indicating that this drug is safe.